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The Hidden Life of the Basal Ganglia by Hagai Bergman
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The Hidden Life of the Basal Ganglia

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The Hidden Life of the Basal Ganglia by Hagai Bergman
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Oct 12, 2021 | ISBN 9780262543118

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    Oct 12, 2021 | ISBN 9780262543118

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  • Oct 12, 2021 | ISBN 9780262367295

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Product Details

Table Of Contents

Preface xi
Acknowledgments xiii
I Introduction and Background 
1 The Basal Ganglia: Why and Where? 3
2 Cellular Anatomy and Biochemistry of the Basal Ganglia 15
3 The Synaptic Connections of the Basal Ganglia Network 27
4 Computational Modeling of Brain and Behavior 39
5 Principles of Neurophysiological Data Acquisition 43
6 Principles of Neurophysiological Analysis 61
II Computational Physiology of the Healthy Basal Ganglia
7 Physiology of the Basal Ganglia 77
8 Basal Ganglia Physiology: The Roads Less Traveled 89
9 Box-and-Arrow Rate Models of the Basal Ganglia 105
10 Reinforcement-Learning Actor/Critic Models of the Basal Ganglia 117
11 Multiple-Critics, Multiobjective Optimization Models of the Basal Ganglia 133
12 The Basal Ganglia as one of many State-to-Action Loops 145
III Computational Physiology of Basal Ganglia Disorders and their Therapy
13 Parkinson’s Disease and other Basal Ganglia-Related Human Disorders 163
14 Animal Models of Parkinson’s Disease 171
15 Physiology of Parkinson’s Disease: Animal Models 179
16 Physiology of Parkinson’s Disease: Human 195
17 Pharmacotherapy of Parkinson’s Disease 203
18 Deep Brain Stimulation Therapy for Parkinson’s Disease 215
19 Closing the Loop on Parkinson’s Disease and Basal Ganglia-Related Disorders 225
IV From the Basal Ganglia and Brain to the Mind 
20 The Basal Ganglia, Free Will, and Human Responsibility 241
Notes 247
References 261
Index 295

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